Two Cases of Opioid-Induced Hyperalgesia in Cancer Patients Treated with Opioids for Pain Management / 한국호스피스완화의료학회지
Korean Journal of Hospice and Palliative Care
; : 100-104, 2019.
Article
en Ko
| WPRIM
| ID: wpr-759852
Biblioteca responsable:
WPRO
ABSTRACT
Opioids are important drugs for the management of severe cancer pain without a ceiling effect. However, opioid administration leads to dose-limiting complications including drowsiness, hallucinations, delirium, respiratory depression, cognitive impairment, seizure, myoclonus, and hyperalgesia. Opioid-induced hyperalgesia (OIH) is a paradoxical phenomenon as opioid exposure increases pain sensitivity. Reducing or stopping opioids, opioid rotation, or co-administration of N-methyl-D-aspartate (NMDA) antagonists have been suggested for the management of OIH. In this study, we report two clinical cases of successful management of OIH in cancer pain patients that were treated with opioids.
Palabras clave
Texto completo:
1
Índice:
WPRIM
Asunto principal:
Insuficiencia Respiratoria
/
Convulsiones
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Fases del Sueño
/
N-Metilaspartato
/
Trastornos del Conocimiento
/
Delirio
/
Manejo del Dolor
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Alucinaciones
/
Hiperalgesia
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Analgésicos Opioides
Límite:
Humans
Idioma:
Ko
Revista:
Korean Journal of Hospice and Palliative Care
Año:
2019
Tipo del documento:
Article