Cerebral Venous Thrombosis Presenting in Pregnancy with Thrombocytosis and Janus Kinase 2 Valine-to-Phenylalanine Mutation
Journal of the Korean Neurological Association
; : 192-195, 2018.
Article
en Ko
| WPRIM
| ID: wpr-766679
Biblioteca responsable:
WPRO
ABSTRACT
A 30-year-old woman in her first pregnancy was admitted with headache and horizontal diplopia indicating left abducens nerve palsy. Brain magnetic resonance imaging revealed a cerebral venous thrombosis. She had thrombocytosis in the peripheral blood, and a genetic test for thrombocytosis revealed the presence of the valine-to-phenylalanine (V617F) mutation of the Janus kinase 2 (JAK2) gene. Treatment with low-molecular-weight heparin resolved her symptoms of headache and diplopia. The presence of genetic disorders such as the JAK2-V617F gene mutation should be assessed in patients with cerebral venous thrombosis and coexisting thrombocytosis.
Palabras clave
Texto completo:
1
Índice:
WPRIM
Asunto principal:
Trombocitosis
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Encéfalo
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Imagen por Resonancia Magnética
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Heparina de Bajo-Peso-Molecular
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Trombosis de la Vena
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Enfermedades del Nervio Abducens
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Diplopía
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Janus Quinasa 2
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Cefalea
Límite:
Adult
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Female
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Humans
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Pregnancy
Idioma:
Ko
Revista:
Journal of the Korean Neurological Association
Año:
2018
Tipo del documento:
Article