Therapeutic effects of the combination of traditional Chinese medicine and western medicine on patients with peptic ulcers / 中南大学学报(医学版)
Journal of Central South University(Medical Sciences)
; (12): 714-718, 2005.
Article
en Zh
| WPRIM
| ID: wpr-813440
Biblioteca responsable:
WPRO
ABSTRACT
OBJECTIVE@#To explore the therapeutic effects and mechanisms of the combination of traditional Chinese medicine and western medicine on patients with peptic ulcers.@*METHODS@#One hundred and twenty patients were randomly divided into 6 groups. Another 10 patients as the control group were confirmed with no peptic ulcers by endoscope, but had digestive tract symptoms. The clinical effects were compared among each group after the one month treatment.@*RESULTS@#The clinical effects of the combination of Jianweiyuyang granules and ranitidine capsules were better than those of western medicine, with improvement in symptoms and syndrome (P 0.05). The combination of Jianweiyuyang granules and ranitidine capsules could significantly upregulate the expression of MUCSAC mRNA (P < 0.01), while downregulate the expression of ETAR mRNA (P < 0.01).@*CONCLUSION@#There is obvious advantage in treating peptic ulcers by the combination of Jianweiyuyang granules and ranitidine capsules, and its mechanisms may be to protect the gastric mucosal barrier by up-regulating the expression of MUCSAC mRNA and to improve the gastric mucosal blood flow by down-regulating the expression of ETAR mRNA.
Texto completo:
1
Índice:
WPRIM
Asunto principal:
Úlcera Péptica
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Ranitidina
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ARN Mensajero
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Cápsulas
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Medicamentos Herbarios Chinos
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Receptores de Endotelina
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Endotelina-1
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Usos Terapéuticos
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Quimioterapia
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Quimioterapia Combinada
Límite:
Adult
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Female
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Humans
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Male
Idioma:
Zh
Revista:
Journal of Central South University(Medical Sciences)
Año:
2005
Tipo del documento:
Article