Research progress on cembranoid type ring diterpenes / 中草药

ABSTRACT

Cembranoid type diterpenes are important natural products which have novel structures and remarkable bioactivities. Cembranoid type diterpenes obtained now included isopropyl type, five, six, seven, eight membered lactone ring, open ring, reducing carbon types, etc, with cytotoxicity and antitumor activity. This paper reviews the structures and bioactivities of 193 cembranoid diterpenes which have been discovered since 2007, providing the scientific evidence for reasonable exploitation and application of cembranoid diterpenes.