Advances in molecular mechanisms of bone invasion by oral cancer / 华西口腔医学杂志
West China Journal of Stomatology
; (6): 221-226, 2021.
Article
en Zh
| WPRIM
| ID: wpr-878434
Biblioteca responsable:
WPRO
ABSTRACT
Bone invasion by oral cancer is a common clinical problem, which affects the choice of treatment and predicts a poor prognosis. Unfortunately, the molecular mechanism of this phenomenon has not been fully elucidated. Current studies have revealed that oral cancer cells modulate the formation and function of osteoclasts through the expression of a series of signal molecules. Many signal pathways are involved in this process, of which receptor activator of nuclear factor-κB ligand/receptor activator of nuclear factor-κB/osteoprotegerin signaling pathway attracted much attention. In this review, we introduce recent progress in molecular mechanisms of bone invasion by oral cancer.
Palabras clave
Texto completo:
1
Índice:
WPRIM
Asunto principal:
Osteoclastos
/
Huesos
/
Resorción Ósea
/
Neoplasias de la Boca
/
Ligando RANK
/
Receptor Activador del Factor Nuclear kappa-B
/
Osteoprotegerina
Tipo de estudio:
Prognostic_studies
Límite:
Humans
Idioma:
Zh
Revista:
West China Journal of Stomatology
Año:
2021
Tipo del documento:
Article