Advances in metabolic engineering for the production of aromatic chemicals / 生物工程学报
Chinese Journal of Biotechnology
; (12): 1771-1793, 2021.
Article
en Zh
| WPRIM
| ID: wpr-878666
Biblioteca responsable:
WPRO
ABSTRACT
Metabolic engineering has been developed for nearly 30 years since the early 1990s, and it has given a great impetus to microbial strain breeding and improvement. Aromatic chemicals are a variety of important chemicals that can be produced by microbial fermentation and are widely used in the pharmaceutical, food, feed, and material industry. Microbial cells can be engineered to accumulate a variety of useful aromatic chemicals in a targeted manner through rational engineering of the biosynthetic pathways of shikimate and the derived aromatic amino acids. This review summarizes the metabolic engineering strategies and biosynthetic pathways for the production of aromatic chemicals developed in the past 30 years, with the aim to provide a valuable reference and promote the research in this field.
Palabras clave
Texto completo:
1
Índice:
WPRIM
Asunto principal:
Ácido Shikímico
/
Vías Biosintéticas
/
Fermentación
/
Ingeniería Metabólica
Idioma:
Zh
Revista:
Chinese Journal of Biotechnology
Año:
2021
Tipo del documento:
Article