Role of exosomes in the development and progression of nonalcoholic fatty liver disease / 临床肝胆病杂志
Journal of Clinical Hepatology
; (12): 2478-2481, 2021.
Article
en Zh
| WPRIM
| ID: wpr-904975
Biblioteca responsable:
WPRO
ABSTRACT
With the increasing incidence rates of metabolic diseases such as obesity and type 2 diabetes, the incidence rate of nonalcoholic fatty liver disease (NAFLD) has also gradually increased year by year. NAFLD has complex underlying pathogeneses which have not yet been fully clarified. As the carrier of intercellular communication, exosomes play an important role in the development and progression of liver diseases. This article summarizes the mechanism of action of exosomes in the pathogenesis of NAFLD and their effect on lipid metabolism, insulin resistance, liver inflammation, and fibrosis, and it is pointed out that exosomes have great potential in the diagnosis and treatment of diseases, which will be the focus of future research.
Texto completo:
1
Índice:
WPRIM
Idioma:
Zh
Revista:
Journal of Clinical Hepatology
Año:
2021
Tipo del documento:
Article