MicroRNA-126 inhibits the proliferation of lung cancer cell line A549
Asian Pacific Journal of Tropical Medicine
; (12): 239-242, 2015.
Article
en Zh
| WPRIM
| ID: wpr-951529
Biblioteca responsable:
WPRO
ABSTRACT
Objective:
To study the role of microRNA-126 in the development of lung cancer.Methods:
The biological function of microRNA-126 was detected using EdU assay and CCK-8 assay; the target gene of microRNA-126 was analyzed using real time RT-PCR and Western blot assay.Results:
In A549 cell line, overexpression of microRNA-126 inhibits the proliferation rate; VEGF is the target gene of microRNA-126; microRNA-126 exerts its function via regulating VEGF protein level.Conclusions:
microRNA-126 inhibits the proliferation in A549 cell line.
Texto completo:
1
Índice:
WPRIM
Idioma:
Zh
Revista:
Asian Pacific Journal of Tropical Medicine
Año:
2015
Tipo del documento:
Article