Research progress of Eubacterium and its metabolite short-chain fatty acids in regulating type 2 diabetes mellitus / 中华预防医学杂志
Chinese Journal of Preventive Medicine
; (12): 120-124, 2023.
Article
en Zh
| WPRIM
| ID: wpr-969853
Biblioteca responsable:
WPRO
ABSTRACT
Intestinal flora and its metabolites are closely related to the progression of type 2 diabetes mellitus(T2DM). Eubacterium is one of the dominant intestinal flora, and its metabolites short-chain fatty acids (SCFAs) play a leading role in regulating intestinal metabolic balance. It has been reported that SCFAs can regulate the secretion of glucagon-like peptide-1, improve the function of pancreatic β cells, participate in bile acids metabolism and regulate the production of inflammatory factors in T2DM. Based on the above research background, this article mainly reviews the relationship between Eubacterium and its metabolite SCFAs and T2DM and its regulatory mechanism.
Texto completo:
1
Índice:
WPRIM
Asunto principal:
Diabetes Mellitus Tipo 2
/
Eubacterium
/
Ácidos Grasos Volátiles
/
Microbioma Gastrointestinal
Límite:
Humans
Idioma:
Zh
Revista:
Chinese Journal of Preventive Medicine
Año:
2023
Tipo del documento:
Article