Absence of mutations associated with resistance to benzimidazole in the beta-tubulin gene of Ascaris suum
Rev. Soc. Bras. Med. Trop
; 53: e20190155, 2020. tab, graf
Article
Dans En
| LILACS
| ID: biblio-1092219
Responsable en Bibliothèque :
BR1.1
ABSTRACT
Abstract INTRODUCTION:
Benzimidazoles are commonly used for the control of veterinary nematodes. Resistance to benzimidazoles has been associated with three single nucleotide polymorphisms in the β-tubulin gene of common nematodes. However, these mutations are infrequent in the genus Ascaris spp.METHODS:
In order to determine mutations associated with benzimidazole resistance in Ascaris suum, worms were collected from slaughtered pigs and a partial region of the β-tubulin gene was sequenced.RESULTS:
All parasites showed the wildtype genotype for codons 167, 198, and 200 of the β-tubulin gene.CONCLUSIONS:
This is the first report of genetic sequences associated with benzimidazole resistance in A. suum.
Texte intégral:
1
Indice:
LILACS
Sujet Principal:
Benzimidazoles
/
Résistance aux substances
/
Ascaris suum
/
Mutation
Type d'étude:
Risk_factors_studies
Limites du sujet:
Animals
langue:
En
Texte intégral:
Rev. Soc. Bras. Med. Trop
Thème du journal:
MEDICINA TROPICAL
Année:
2020
Type:
Article