Interaction of Biomphalaria cells in primary cultures with Schistosoma mansoni sporocysts
Rev. Soc. Bras. Med. Trop
; 53: e20200257, 2020. graf
Article
de En
| SES-SP, ColecionaSUS, LILACS
| ID: biblio-1136878
Bibliothèque responsable:
BR1.1
ABSTRACT
Abstract INTRODUCTION:
Biomphalaria snails may display varying levels of susceptibility to Schistosoma mansoni infection. We have been developing an in vitro model to study the interaction between the snail and the parasite, using tissue-derived cell cultures from Biomphalaria.METHODS:
The digestive gland- and kidney-derived cells from primary cultures of resistant (B. tenagophila Taim) and susceptible (B. tenagophila HM and B. glabrata BH) strains of Biomphalaria were exposed to S. mansoni sporocysts.RESULTS:
S. mansoni sporocysts were surrounded and encapsulated exclusively by cells derived from the digestive gland (DG) of B. tenagophila Taim. The process was followed by a marked decrease in the number of free sporocysts in the culture medium. The morphological characteristics of DG-derived cells in culture have been described.CONCLUSIONS:
Cells derived from DG (but not SK) primary cultures of B. tenagophila Taim may participate in S. mansoni sporocyst control.Mots clés
Texte intégral:
1
Indice:
LILACS
Sujet Principal:
Biomphalaria
/
Schistosomiase à Schistosoma mansoni
Type d'étude:
Prognostic_studies
Limites du sujet:
Animals
langue:
En
Texte intégral:
Rev. Soc. Bras. Med. Trop
Thème du journal:
MEDICINA TROPICAL
Année:
2020
Type:
Article