Effect of rape flower on benign prostatic hyperplasia in rats
Braz. J. Pharm. Sci. (Online)
; 58: e18785, 2022. graf
Article
Dans En
| LILACS
| ID: biblio-1364421
Responsable en Bibliothèque :
BR40.1
Localisation: BR40.1
ABSTRACT
We were carried out to investigate the efficacy of Rape (Rapeseed, Brassica napus L.) flower on BPH (benign prostatic hyperplasia) in rats. We found that the extract from Rape flower prevented hyperplasia in testosterone-induced BPH model, the relevant animal model of human BPH. Extract reduced the weight of prostate and induced significantly cell apoptosis in prostate in BPH model. In addition, the extract controlled expression of TGF-ß1 in prostate gland and promoted urinary output in dose-dependence in BPH model. Our data provide that Rape flower may be useful for treatment of BPH
Texte intégral:
1
Indice:
LILACS
Sujet Principal:
Hyperplasie de la prostate
/
Efficacité en Santé Publique
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Brassica napus
/
Fleurs
Limites du sujet:
Animals
langue:
En
Texte intégral:
Braz. J. Pharm. Sci. (Online)
Thème du journal:
Farmacologia
/
Teraputica
/
Toxicologia
Année:
2022
Type:
Article