Angiosarcoma in HIV-negative patients is not associated with HHV-8
An. bras. dermatol
; 91(6): 738-741, Nov.-Dec. 2016. tab, graf
Article
Dans En
| LILACS
| ID: biblio-837975
Responsable en Bibliothèque :
BR1.1
ABSTRACT
Abstract BACKGROUND:
Angiosarcoma is an aggressive, malignant neoplasm of vascular or lymphatic origin. Herpes virus 8 (HHV-8) is a member of the herpes family with a tropism for endothelial cells and it has been proven to induce vascular neoplasms, such as Kaposi's sarcoma. The role of HHV-8 in the pathogenesis of angiosarcoma has not been well defined.OBJECTIVE:
To investigate the relationship between the presence of HHV-8 and angiosarcoma.METHODS:
In this study, the team investigated the relationship between the presence of HHV-8, as determined by polymerase chain reaction, and angiosarcoma, using samples from patients with epidemic Kaposi's sarcoma as controls.RESULTS:
While all control cases with epidemic Kaposi's sarcoma were positive for HHV-8, none of the angiosarcoma cases was.CONCLUSION:
These findings support most previous studies that found no association between HHV-8 and angiosarcoma.
Texte intégral:
1
Indice:
LILACS
Sujet Principal:
Sarcome de Kaposi
/
Tumeurs cutanées
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Infections opportunistes liées au SIDA
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Séronégativité VIH
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Herpèsvirus humain de type 8
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Hémangiosarcome
Type d'étude:
Observational_studies
/
Risk_factors_studies
Limites du sujet:
Aged
/
Aged80
/
Female
/
Humans
/
Male
Pays comme sujet:
America do sul
/
Brasil
langue:
En
Texte intégral:
An. bras. dermatol
Thème du journal:
DERMATOLOGIA
Année:
2016
Type:
Article