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Effect of fluoride on salivary immunoglobulins and sialic acid
Güzel, Kadriye Görkem Ulu; Kirzioglu, Zuhal; Adiloglu, Ali Kudret; Ertürk, Münciye Semra Özay.
Affiliation
  • Güzel, Kadriye Görkem Ulu; Adnan Menderes University. Faculty of Dentistry. Department of Pediatric Dentistry. Aydin. TR
  • Kirzioglu, Zuhal; Adnan Menderes University. Faculty of Dentistry. Department of Pediatric Dentistry. Aydin. TR
  • Adiloglu, Ali Kudret; Adnan Menderes University. Faculty of Dentistry. Department of Pediatric Dentistry. Aydin. TR
  • Ertürk, Münciye Semra Özay; Adnan Menderes University. Faculty of Dentistry. Department of Pediatric Dentistry. Aydin. TR
Rev. Assoc. Med. Bras. (1992, Impr.) ; Rev. Assoc. Med. Bras. (1992, Impr.);63(4): 320-323, Apr. 2017. tab, graf
Article de En | LILACS | ID: biblio-842557
Bibliothèque responsable: BR1.1
ABSTRACT
Summary

Objective:

The aim of our study was to evaluate the effect of fluoride on salivary immunoglobulin and sialic acid levels in children with dental fluorosis and healthy teeth who live in places with high fluoride concentration in drinking water.

Method:

Fifty-one (51) healthy children between 6 and 12 years old with no caries were randomly selected from primary schools enrolled in the dental-care program operated by the Department of Pediatric Dentistry. The children were divided into two groups group I comprised 26 children with dental fluorosis [Thylstrup-Fejerskov Dental Fluorosis Index (TFI) = 4] who lived in Isparta (2.7-2.8 ppm), and group II consisted of 25 children without dental fluorosis who were born in low-fluoride areas and had lived in Isparta for only the previous two years. Stimulated and unstimulated saliva were collected and analyzed for fluoride, salivary immunoglobulins and sialic acid levels.

Results:

Sialic acid level was correlated negatively with age. Levels of secretory immunoglobulin A (sIgA) and secretory immunoglobulin G (sIgG) were higher in children with dental fluorosis compared with those in group II, although these differences were not significant.

Conclusion:

Increased sIgA and sIgG levels may arrest the progression of caries in subjects with dental fluorosis. Given the risks of dental fluorosis, further studies of the effects of different fluoride levels in drinking water on salivary composition of children with mixed dentition are needed to confirm the results of our study and to provide data for comparison.
Sujet(s)
Mots clés

Texte intégral: 1 Indice: LILACS Sujet Principal: Salive / Immunoglobuline A sécrétoire / Immunoglobuline G / Cariostatiques / Acide N-acétyl-neuraminique / Fluorures / Fluorose dentaire Type d'étude: Etiology_studies / Evaluation_studies / Observational_studies / Risk_factors_studies Limites du sujet: Child / Female / Humans / Male langue: En Texte intégral: Rev. Assoc. Med. Bras. (1992, Impr.) Thème du journal: Educa‡Æo em Sa£de / GestÆo do Conhecimento para a Pesquisa em Sa£de / MEDICINA Année: 2017 Type: Article

Texte intégral: 1 Indice: LILACS Sujet Principal: Salive / Immunoglobuline A sécrétoire / Immunoglobuline G / Cariostatiques / Acide N-acétyl-neuraminique / Fluorures / Fluorose dentaire Type d'étude: Etiology_studies / Evaluation_studies / Observational_studies / Risk_factors_studies Limites du sujet: Child / Female / Humans / Male langue: En Texte intégral: Rev. Assoc. Med. Bras. (1992, Impr.) Thème du journal: Educa‡Æo em Sa£de / GestÆo do Conhecimento para a Pesquisa em Sa£de / MEDICINA Année: 2017 Type: Article