Sickle cell trait in the Eastern Province of Saudi Arabia: effect of concurrent alpha-thalassemia
Saudi Medical Journal. 1987; 8 (3): 253-8
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| IMEMR
| ID: emr-114503
Bibliothèque responsable:
EMRO
The proportions of sickle haemoglobin in the peripheral blood were determined in 126 asymptomatic sickle cell trait parents of SS cohort babies. The sickle cell haemoglobin [Hb S] levels ranged between 18 and 48% and the values below 38% are presumably due to the interaction of various types of alpha thalassaemia genes with sickle cell genes. The haematological paramers correlated well with the amounts of Hb S in the red blood cells and the comparison of these erythrocytic indices with sickle cell traits from north western province revealed inter-province variations in haematological values, especially the mean cell volume [MCV] and mean cell haemoglobin [MCH]. These two parameters were significantly reduced in the sickle cell heterozygotes from the Eastern province as compared with those from the north western province, in particular the Khaiber area, for which the explanation remains obscure
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Indice:
IMEMR
Sujet Principal:
Thalassémie
langue:
En
Texte intégral:
Saudi Med. J.
Année:
1987