[Comparison of the intranasal and intraperitoneal injection of MPTP on density of dark neurons in pars compacta of substantia nigra in animal model of Parkinson's disease]
Journal of Gorgan University of Medical Sciences. 2015; 17 (3): 55-62
Dans Fa
| IMEMR
| ID: emr-173784
Responsable en Bibliothèque :
EMRO
ABSTRACT
Background and Objective:
Parkinson disease [PD] is the second most common neurologic disorder that results following degeneration of dopaminergic neurons in the pars compacta of substintia nigra [SNc]. The 1-methyl-1,2,3,6-tetrahydropiridine [MPTP] is a chemical neurotoxin that widely used in animal models of PD. This study was carried out to evaluate the numerical density of dark neurons [DNs] in the SNc in mice subjected to intraperitoneal and intranasal injection of different doses of MPTP
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Indice:
IMEMR
Sujet Principal:
Administration par voie nasale
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Substantia nigra
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1-Méthyl-4-phényl-1,2,3,6-tétrahydropyridine
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Modèles animaux
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Pars compacta
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Injections péritoneales
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Souris de lignée BALB C
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Neurones
Limites du sujet:
Animals
langue:
Fa
Texte intégral:
J. Gorgan Univ. Med. Sci.
Année:
2015