Effects of blood lipid stability on progression of carotid atherosclerosis
Pakistan Journal of Medical Sciences. 2017; 33 (3): 599-602
de En
| IMEMR
| ID: emr-188034
Bibliothèque responsable:
EMRO
Objective: To evaluate the effects of blood lipid stability on progression of carotid atherosclerosis
Methods: A total of 416 patients who had physical examination in our hospital annually from January 2010 to December 2015 were selected and divided into a progression group [n=216] and a non-progression group [n=200] according to the intima-media thickness measured by carotid ultrasound. The levels of lipidrelated parameters within five years were retrospectively analyzed to calculate the smoothness index [SI = x/s]
Results: The cross-sectional TG, HDL-C, ApoAI, ApoB, ApoE and Lpa levels were similar in the two groups [p>0.05]. The non-progression group had significantly higher TC [[4.15 +/- 0.82 vs. 4.50 +/- 1.04] mmol/L] and LDL-C [[2.53 +/- 0.76 vs. 2.99 +/- 1.03] mmol/L] levels than those of the progression group [p<0.05].The progression group had significantly lower TC SI [5.29 +/- 1.28 vs. 5.65 +/- 1.76], TG SI [2.13 +/- 0.71 vs. 2.79 +/- 0.82], LDL-C SI [3.66 +/- 1.17 vs. 4.36 +/- 1.58], ApoB SI [3.37 +/- 0.88 vs. 3.62 +/- 0.95] and Lpa SI [1.53 +/- 0.49 vs. 1.62 +/- 0.43] than those of the non-progression group [p<0.05]
Conclusion: Compared with cross-sectional results, SI was better correlated with the progression of atherosclerosis. The progression group had lower SI values
Methods: A total of 416 patients who had physical examination in our hospital annually from January 2010 to December 2015 were selected and divided into a progression group [n=216] and a non-progression group [n=200] according to the intima-media thickness measured by carotid ultrasound. The levels of lipidrelated parameters within five years were retrospectively analyzed to calculate the smoothness index [SI = x/s]
Results: The cross-sectional TG, HDL-C, ApoAI, ApoB, ApoE and Lpa levels were similar in the two groups [p>0.05]. The non-progression group had significantly higher TC [[4.15 +/- 0.82 vs. 4.50 +/- 1.04] mmol/L] and LDL-C [[2.53 +/- 0.76 vs. 2.99 +/- 1.03] mmol/L] levels than those of the progression group [p<0.05].The progression group had significantly lower TC SI [5.29 +/- 1.28 vs. 5.65 +/- 1.76], TG SI [2.13 +/- 0.71 vs. 2.79 +/- 0.82], LDL-C SI [3.66 +/- 1.17 vs. 4.36 +/- 1.58], ApoB SI [3.37 +/- 0.88 vs. 3.62 +/- 0.95] and Lpa SI [1.53 +/- 0.49 vs. 1.62 +/- 0.43] than those of the non-progression group [p<0.05]
Conclusion: Compared with cross-sectional results, SI was better correlated with the progression of atherosclerosis. The progression group had lower SI values
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Indice:
IMEMR
langue:
En
Texte intégral:
Pak. J. Med. Sci.
Année:
2017