Reacción por drogas con eosinofilia y síntomas sistémicos (síndrome de DRESS): Estudio retrospectivo de nueve casos / Dress syndrome: Report of nine cases
Rev. méd. Chile
; 143(5): 577-583, ilus, tab
Article
de Es
| LILACS
| ID: lil-751702
Bibliothèque responsable:
CL1.1
ABSTRACT
Background:
DRESS Syndrome (Drug Reaction with Eosinophilia and Systemic Symptoms) is an uncommon disease caused by drugs. It is characterized by a polymorphic disseminated eruption with fever and multiple organ dysfunction.Aim:
To report the etiology, characteristics, treatment, prognosis, and follow up of patients with DRESS Syndrome admitted to a clinical hospital. Material andMethods:
Review of medical records of patients admitted for drug reactions, selecting those patients complying with clinical criteria for DRESS Syndrome. Drugs used during three months prior to the onset of symptoms were evaluated as possible causes of the disease.Results:
Nine patients aged 16 to 68 years (six males) complied with the clinical criteria for the disease. The causative medications were carbamazepine in three patients, phenytoin in three, antituberculous drugs in two and amoxicillin in one. All were treated with systemic steroids with a complete clinical resolution.Conclusions:
DRESS syndrome is usually underdiagnosed and has a good response to systemic steroids.Mots clés
Texte intégral:
1
Indice:
LILACS
Sujet Principal:
Dexaméthasone
/
Prednisone
/
Syndrome d'hypersensibilité médicamenteuse
Type d'étude:
Diagnostic_studies
/
Etiology_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limites du sujet:
Adolescent
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Adult
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Aged
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Female
/
Humans
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Male
langue:
Es
Texte intégral:
Rev. méd. Chile
Thème du journal:
MEDICINA
Année:
2015
Type:
Article