Clinical assessment of 252Californium neutron intracavitary brachytherapy using a two-channel Y applicator combined with external beam radiotherapy for endometrial cancer
Clinics
; 71(1): 10-16, Jan. 2016. tab, graf
Article
de En
| LILACS
| ID: lil-771947
Bibliothèque responsable:
BR1.1
ABSTRACT
OBJECTIVE:
The aim of this study was to determine the efficacy of 252Californium neutron intracavitary brachytherapy using a two-channel Y applicator combined with external beam radiotherapy for the treatment of endometrial cancer.METHODS:
Thirty-one patients with stage I-III endometrial cancer were recruited for this study. The stage I patients received only 252Californium neutron intracavitary brachytherapy with a two-channel applicator. The stage II and III patients received both 252Californium neutron intracavitary brachytherapy using a two-channel applicator and parallel-opposed whole pelvic radiotherapy.RESULTS:
The five-year local control rate was 80.6% (25/31), the overall survival rate was 51.6% (16/31), and the disease-free survival rate was 54.8% (17/31). The incidence of serious late complications was 12.9% (4/31).CONCLUSIONS:
252Californium neutron intracavitary brachytherapy using a two-channel applicator combined with external beam radiotherapy was effective for treating endometrial cancer and the incidence of serious late complications related to this combination was within an acceptable range.Mots clés
Texte intégral:
1
Indice:
LILACS
Sujet Principal:
Curiethérapie
/
Adénocarcinome
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Californium
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Tumeurs de l'endomètre
Type d'étude:
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limites du sujet:
Adult
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Aged
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Female
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Humans
langue:
En
Texte intégral:
Clinics
Thème du journal:
MEDICINA
Année:
2016
Type:
Article