The effect of prenatal exposure to 1800 MHz electromagnetic field on calcineurin and bone development in rats
Acta cir. bras
; 31(2): 74-83, Feb. 2016. tab, graf
Article
Dans En
| LILACS
| ID: lil-775567
Responsable en Bibliothèque :
BR1.1
ABSTRACT
PURPOSE:
To investigated the effects of exposure to an 1800 MHz electromagnetic field (EMF) on bone development during the prenatal period in rats.METHODS:
Pregnant rats in the experimental group were exposed to radiation for six, 12, and 24 hours daily for 20 days. No radiation was given to the pregnant rats in the control group. We distributed the newborn rats into four groups according to prenatal EMF exposure as follows Group 1 was not exposed to EMF; groups 2, 3, and 4 were exposed to EMF for six, 12, and 24 hours a day, respectively. The rats were evaluated at the end of the 60th day following birth.RESULTS:
Increasing the duration of EMF exposure during the prenatal period resulted in a significant reduction of resting cartilage levels and a significant increase in the number of apoptotic chondrocytes and myocytes. There was also a reduction in calcineurin activities in both bone and muscle tissues. We observed that the development of the femur, tibia, and ulna were negatively affected, especially with a daily EMF exposure of 24 hours.CONCLUSION:
Bone and muscle tissue development was negatively affected due to prenatal exposure to 1800 MHz radiofrequency electromagnetic field.
Texte intégral:
1
Indice:
LILACS
Sujet Principal:
Effets différés de l'exposition prénatale à des facteurs de risque
/
Développement osseux
/
Calcineurine
/
Champs électromagnétiques
Type d'étude:
Prognostic_studies
Limites du sujet:
Animals
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Female
/
Humans
/
Male
langue:
En
Texte intégral:
Acta cir. bras
Thème du journal:
CIRURGIA GERAL
/
Procedimentos Cir£rgicos Operat¢rios
Année:
2016
Type:
Article