2-CdA in the treatment of hairy cell leukaemia.
Article
Dans En
| IMSEAR
| ID: sea-91940
ABSTRACT
INTRODUCTION:
Hairy cell leukaemia (HCL) is a rare lymphoproliferative disorder. Treatment options available are splenectomy, interferon, DCF and 2-CdA. 2-CdA is considered to have curative potential as proved by the other studies.METHODS:
We gave 2-CdA in a dose of 0.09/kg/day as a continuous infusion in sixteen patients of hairy cell leukaemia.RESULTS:
Three patients developed neutropenia post transfusion. At the end of three months all patients were in remission. Two patients relapsed at the median follow-up of 15 months.CONCLUSION:
2-CdA in HCL can achieve complete remission, prolonged survival and care as well.
Texte intégral:
1
Indice:
IMSEAR
Sujet Principal:
Femelle
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Humains
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Mâle
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Leucémie à tricholeucocytes
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Chloro-2 adénosine
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Désoxyadénosine
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Taux de survie
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Résultat thérapeutique
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Adulte
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Adulte d'âge moyen
langue:
En
Année:
2001
Type:
Article