Design and development of sustained and controlled release preparations in traditional Chinese medicine based on quality by design( QbD) / 中国中药杂志
China Journal of Chinese Materia Medica
; (24): 4317-4321, 2019.
Article
Dans Zh
| WPRIM
| ID: wpr-1008196
Responsable en Bibliothèque :
WPRO
ABSTRACT
In this paper,the design and development of sustained and controlled release preparations in traditional Chinese medicine( TCM) based on quality by design( QbD) was put forward,aiming at the current situation that the final product quality is affected by multiple factors during the development of sustained and controlled release preparations in TCM. The important development of sustained and controlled release preparations in western medicine in recent years was summarized. According to the complex process of TCM,the concept of QbD was proposed to design and develop sustained and controlled release preparations in TCM. QbD concept was used to analyze the complex factors affecting sustained and controlled release preparations in TCM,and determine the high risk factors affecting the quality of the final product. The high risk factors were controlled from the process to achieve the goal of quality control.This article could provide research ideas for the sustained and controlled release preparations with complex components in TCM,so as to promote the research and development of sustained and controlled release preparations in TCM.
Texte intégral:
1
Indice:
WPRIM
Sujet Principal:
Contrôle de qualité
/
Médicaments issus de plantes chinoises
/
Préparations à action retardée
/
Médecine traditionnelle chinoise
langue:
Zh
Texte intégral:
China Journal of Chinese Materia Medica
Année:
2019
Type:
Article