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Periostin-a potential molecular marker for early diagnosis of disease / 中国药理学通报
Chinese Pharmacological Bulletin ; (12): 650-654, 2022.
Article de Zh | WPRIM | ID: wpr-1014202
Bibliothèque responsable: WPRO
ABSTRACT
Periostin (POSTN), an evolutionary conserved and secreted extracellular matrix protein, can be easily detected by humoral samples such as blood, urine, interstitial fluid etc., which was firstly found in bone tissues.POSTN is expressed in various tissues and its expression level is closely related to oc¬currence and development of various diseases, which will be a potential molecular marker in early diagnosis of diseases.'Hie paper systematically summarizes the relationship of the expres¬ sion level of POSTN and some diseases including myocardial in¬farction, vascular calcification, diseases related to bone metabo¬lism, chronic nephrosis and various cancers, and explores its function as well as mechanism, which provides scientific basis for the early diagnostic kits or new drug development of diseases based on POSTN.
Mots clés
Texte intégral: 1 Indice: WPRIM langue: Zh Texte intégral: Chinese Pharmacological Bulletin Année: 2022 Type: Article
Texte intégral: 1 Indice: WPRIM langue: Zh Texte intégral: Chinese Pharmacological Bulletin Année: 2022 Type: Article