Your browser doesn't support javascript.
loading
The application of ultrasound bronchoscopy combined with mNGS in the etiological diagnosis of pneumonia with poor absorption and dissipation / 重庆医学
Chongqing Medicine ; (36): 193-197, 2024.
Article de Zh | WPRIM | ID: wpr-1017463
Bibliothèque responsable: WPRO
ABSTRACT
Objective To explore the clinical value of ultrasound bronchoscopy combined with met-agenomic next-generation sequencing(mNGS)in the etiological diagnosis of pneumonia with poor absorption and dissipation.Methods The clinical data of the patients with pneumonia with poor absorption and dissipa-tion in this hospital from January 2022 to February 2023 were retrospectively collected.Among them,73 cases received the endobronchial ultrasound guided tranbronchial needle aspiration(EBUS-TBNA)and 36 cases re-ceived endobronchial ultrasound transbronchial lung biopsy using guide sheath(EBUS-GS-TBLB).The distri-bution of causes and incidence of examination related complications were analysed.Results The results of ul-trasound bronchoscopy combined with mNGS examination showed that the benign lesions accounted for 33.03%,mainly chronic inflammation(9.17%)and infectious disease(20.18%),and tuberculosis was the main cause of infectious diseases(7.34%).The malignant lesions accounted for 57.80%,mainly adenocarcinoma(28.44%).The diagnostic positive rate was 90.83%,and no definite diagnosis accounted for 9.17%.There was no statistically significant difference in the diagnostic positive rate between the patients receiving EBUS-TBNA combined with mNGS examination and the patients receiving EBUS-GS-TBLB combined with mNGS examination(94.52%vs.83.33%,P>0.05),and there was no statistically significant difference in the inci-dence rates of complications such as less bleeding,anoxia,pneumothorax and delayed resuscitation.No serious complications such as mediastinal emphysema,large vessel injury,shock and death were observed in all pa-tients.Conclusion Ultrasound bronchoscopy combined with mNGS has the characteristics of high diagnostic positive rate and few complications in the etiological diagnosis of pneumonia with poor absorption and dissipa-tion.It can help clinical physicians clarify the diagnosis as soon as possible,and may become a new method for diagnosing respiratory system diseases in recent years.
Mots clés
Texte intégral: 1 Indice: WPRIM langue: Zh Texte intégral: Chongqing Medicine Année: 2024 Type: Article
Texte intégral: 1 Indice: WPRIM langue: Zh Texte intégral: Chongqing Medicine Année: 2024 Type: Article