Study on the stability of different fat emulsions in parenteral nutrition / 中华临床营养杂志
Chinese Journal of Clinical Nutrition
; (6): 290-293,306, 2023.
Article
de Zh
| WPRIM
| ID: wpr-1024650
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WPRO
ABSTRACT
Objective:To investigate the stability of fat emulsions after the preparation of parenteral nutrient solution under different storage conditions.Methods:Standardized parenteral nutrient solution was used to prepare a total of 24 bags of nutrient solution with the same formula, except for that Group A (12 bags) contains 20% of medium and long chain fat emulsion (C6-24) while Group B contains 20% of C8-24. The preparations were stored under 2-8℃, 23-25℃, and 35-37℃ and were examined at 24h, 48h and 72h after preparation. The appearance, average size of fat particles, pH value of nutrient solution, and lipid peroxidation were investigated.Results:After storage at 4℃, 25℃ and 36℃ for 24h, 48h and 72h respectively, both groups of preparations showed no obvious change in appearance. There was no significant difference in pH ( P>0.05) nor lipid peroxidation ( P>0.05). Conclusion:Both kinds of fat emulsion are stable in terms of pH value, fat particle size and lipid peroxidation, and can be used for patients receiving intravenous nutrition support.
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Indice:
WPRIM
langue:
Zh
Texte intégral:
Chinese Journal of Clinical Nutrition
Année:
2023
Type:
Article