Progression of research into the relationship between pyroptosis and atherosclerosis / 中国比较医学杂志
Chinese Journal of Comparative Medicine
; (6): 146-150, 2024.
Article
Dans Zh
| WPRIM
| ID: wpr-1025103
Responsable en Bibliothèque :
WPRO
ABSTRACT
Pyroptosis is a programmed mode of cell death.Activated caspase-1 can induce the occurrence of pyroptosis,promote the release of inflammatory factors,and trigger a violent inflammatory response.Depending on the type of caspase involved,pyroptosis can be divided into a caspase-1-mediated typical inflammasome pathway and a human caspase-4/5(or mouse caspase-11)-mediated atypical inflammasome pathway.In recent years,studies have found that pyroptosis is closely related to the occurrence,development,and prognosis of atherosclerosis.This article reviews the roles and mechanisms of endothelial cells,vascular smooth muscle cells,and macrophage cells in the occurrence and development of atherosclerosis,with the aim of promoting new ideas for research into the pathogenesis,diagnosis,and treatment of atherosclerosis
Texte intégral:
1
Indice:
WPRIM
langue:
Zh
Texte intégral:
Chinese Journal of Comparative Medicine
Année:
2024
Type:
Article