Characteristics of acute symptomatic seizures and autoimmune associated epilepsy secondary to autoimmune encephalitis / 中华神经医学杂志

ABSTRACT

Autoimmune encephalitis (AE) is closely related to epileptic seizure, which is a common clinical manifestation or even the only symptom at acute phase of AE. Most patients do not develop seizures after treatment at acute or subacute stages, and these patients are classified as acute symptomatic seizures secondary to AE (ASSAE). Only a minority of patients will eventually develop autoimmune associated epilepsy (AAE). At present, no unified standard for clinical diagnosis is noted between ASSAE and AAE, but some differences exist in definition, pathogenesis, diagnosis and treatment. This paper summarizes the similarities and differences between ASSAE and AAE in the above aspects, aiming at providing help for clinicians to differentiate the diagnosis of the two diseases.