Antimicrobial Prophylaxis Using a 2nd Generation Cephalosporin after Laparoscopic Colorectal Resection: A Randomized Trial of 1-day vs. 3-day
Journal of the Korean Surgical Society
; : 385-389, 2010.
Article
Dans Ko
| WPRIM
| ID: wpr-10361
Responsable en Bibliothèque :
WPRO
ABSTRACT
PURPOSE:
We performed this study to compare 1-day group using a 2nd generation cephalsporin with 3-day group for evaluating hospital acquired infection.METHODS:
The patients underwent laparoscopic colorectal surgery at Korea University Medical Center Anam Hospital, from August, 2007 to June, 2008. They were randomly allocated to 2 groups 1-day or 3-day group. A 2nd generation cephalosporin was administered within 1 hour before surgery with 12-hour intervals. In cases of suspected infection, further studies were done to identify infection.RESULTS:
The study included 154 patients (1-day group - 78, vs. 3-day group - 76). No differences were noted between the 2 groups in age, body mass index, smoking, diabetes mellitus, corticosteroid-use were noted. Gender (P=0.011) and mean operative time (P=0.047) between the 2 groups were different. The preventive rates of infection were 87.18% in the 1-day group compared with 82.89% in the 3-day group (P=0.456).CONCLUSION:
Our prospective randomized control study concluded that there were no differences between the 1-day and 3-day group in hospital acquired infection. We could come to the conclusion that 1-day antimicrobial agent in laparoscopic colorectal surgery would be adequate in preventing infection.
Texte intégral:
1
Indice:
WPRIM
Sujet Principal:
Fumée
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Fumer
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Indice de masse corporelle
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Études prospectives
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Chirurgie colorectale
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Diabète
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Centres hospitaliers universitaires
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Durée opératoire
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Corée
Type d'étude:
Clinical_trials
/
Observational_studies
Limites du sujet:
Humans
Pays comme sujet:
Asia
langue:
Ko
Texte intégral:
Journal of the Korean Surgical Society
Année:
2010
Type:
Article