A Case of IgG4-Related Lung Disease Mimicking Non-Specific Interstitial Pneumonia / 대한내과학회지
Korean Journal of Medicine
; : 308-312, 2015.
Article
de Ko
| WPRIM
| ID: wpr-103789
Bibliothèque responsable:
WPRO
ABSTRACT
Immunoglobulin (Ig) G4-related disease is a recently described systemic inflammatory disease characterized by high serum IgG4 concentrations and sclerosing inflammation of numerous IgG4-positive plasma cells that responds favorably to steroid treatment. Although initial description of this disorder focused on its pancreatic presentation, it has become apparent that it is a systemic disease. In this report, we describe a case of IgG4-related lung disease presenting as non-specific interstitial pneumonia in a 78-year-old male with interstitial lung disease. Pathological examination through video-assisted thoracic surgery showed a non-specific interstitial pneumonia pattern and numerous (> 50/high-power field) infiltrating IgG4-positive plasma cells. Laboratory tests also revealed a high serum IgG4 concentration. Prednisolone therapy was initiated and his symptoms and reticular opacity improved after two months of treatment.
Mots clés
Texte intégral:
1
Indice:
WPRIM
Sujet Principal:
Plasmocytes
/
Immunoglobuline G
/
Immunoglobulines
/
Prednisolone
/
Pneumopathies interstitielles
/
Chirurgie thoracique vidéoassistée
/
Inflammation
/
Maladies pulmonaires
Limites du sujet:
Aged
/
Humans
/
Male
langue:
Ko
Texte intégral:
Korean Journal of Medicine
Année:
2015
Type:
Article