Antimicrobial Persistence of Silver Diamine Fluoride and Silver Fluoride against Streptococcus mutans

ABSTRACT

Purpose@#To evaluate the antimicrobial persistence of silver diamine fluoride (SDF) and silver fluoride (AgF) on Streptococcus mutans. @*Materials and Methods@#An in vitro experiment was conducted to observe changes in the diameter of the inhibition zone of various materials, including AgF (Riva Star Aqua™ step 1; SDI), potassium iodine (Riva star aqua™ step 2;SDI), Fluor protector® (FP, Ivoclar Vivadent), SDF (Riva star™ step 1; SDI), Ampicillin (Sigma-Aldrich), Amphotericin B (Nexstar) and negative control on S. mutans.Result: SDF, AgF and FP exhibited significant antimicrobial persistence over the 4 weeks period (P<0.05). At day 28, the diameter of inhibition zone was larger in SDF than in AgF. @*Conclusion@#SDF and AgF have significant antibacterial durability against bacteria commonly associated with dental caries, with the antimicrobial effect lasting for at least 4 weeks. Further clinical studies are needed to validate these findings in vivo.