Treatment of Clival Giant Cell Tumor: A Case Report and Literature Review
Brain Tumor Research and Treatment
; : 132-140, 2024.
Article
de En
| WPRIM
| ID: wpr-1042271
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WPRO
ABSTRACT
Giant cell tumors (GCTs) are locally aggressive primary bone tumors of osteoclast-like cells. Most GCTs occur within the long bones, and primary GCTs involving the clivus are extremely rare. We present the case of an 18-year-old boy with binocular horizontal diplopia with an insidious onset who was found to have a hypointense enhancing mass involving the clivus and left side dorsum sellae on magnetic resonance images. The tumor was completely resected via an endoscopic endonasal transclival approach, and histopathologic examination via immunohistochemistry indicated a GCT. The patient’s left abducens nerve palsy improved slightly after surgery. Because of the rarity of GCTs, there is no consensus about the definitive treatment protocol. However, we suggest that gross total resection is the treatment of choice, and denosumab plays a critical role in patients with subtotal resection.
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WPRIM
langue:
En
Texte intégral:
Brain Tumor Research and Treatment
Année:
2024
Type:
Article