An Epidemiological Analysis of Hepatitis A Virus Serologic Markers during the Recent Four Years in Korea / 대한진단검사의학회지
The Korean Journal of Laboratory Medicine
; : 563-569, 2009.
Article
de Ko
| WPRIM
| ID: wpr-106758
Bibliothèque responsable:
WPRO
ABSTRACT
BACKGROUND: To establish effective preventive measures for hepatitis A virus (HAV) infection, a nationwide epidemiologic study on seroprevalence of anti-HAV and the disease prevalence is needed. The aim of this study was to analyze the recent sero-epidemiological changes of hepatitis A markers in Korea. METHODS: The results of 11,068 anti-HAV total and 32,360 anti-HAV IgM tests by electro-chemiluminescence immunoassay (ECLIA) that had been requested in recent four years (2005-2008) to a reference medical laboratory from 1,699 institutions nationwide were retrospectively analyzed according to the distribution of year, sex, and age groups. RESULTS: The overall positive rate of anti-HAV total was 62.8%. The overall positive rate of anti-HAV IgM was 11.0%, showing a significantly increasing trend by year: 7.7%, 10.9%, 8.9%, and 14.3% in 2005, 2006, 2007, and 2008, respectively (P or =21 yr. Conclusion: In accordance with a decreasing sero-positivity of anti-HAV total, the prevalence of acute hepatitis A virus infection has been considerably increased during the recent four years in the age groups of > or =21 yr. The results of this study could be used effectively as a basic data for establishing effective preventive measures for hepatitis A including vaccination in these susceptible age groups.
Mots clés
Texte intégral:
1
Indice:
WPRIM
Sujet Principal:
Facteurs temps
/
Immunoglobuline M
/
Test ELISA
/
Marqueurs biologiques
/
Facteurs sexuels
/
Études rétrospectives
/
Virus de l'hépatite A
/
Anticorps de l'hépatite A
/
République de Corée
/
Hépatite A
Type d'étude:
Observational_studies
/
Risk_factors_studies
Limites du sujet:
Adult
/
Female
/
Humans
/
Male
Pays comme sujet:
Asia
langue:
Ko
Texte intégral:
The Korean Journal of Laboratory Medicine
Année:
2009
Type:
Article