Hepatitis E virus as an emerging zoonotic pathogen
Journal of Veterinary Science
; : 1-11, 2016.
Article
Dans En
| WPRIM
| ID: wpr-110771
Responsable en Bibliothèque :
WPRO
ABSTRACT
Hepatitis E outbreaks are a serious public health concern in developing countries. The disease causes acute infections, primarily in young adults. The mortality rate is approximately 2%; however, it can exceed 20% in pregnant women in some regions in India. The causative agent, hepatitis E virus (HEV), has been isolated from several animal species, including pigs. HEV genotypes 3 and 4 have been isolated from both humans and animals, and are recognized as zoonotic pathogens. Seroprevalence studies in animals and humans indirectly suggest that HEV infections occur worldwide. The virus is primarily transmitted to humans via undercooked animal meats in developed countries. Moreover, transfusion- and transplantation-mediated HEV infections have recently been reported. This review summarizes the general characteristics of hepatitis E, HEV infection status in animals and humans, the zoonotic transmission modes of HEV, and HEV vaccine development status.
Texte intégral:
1
Indice:
WPRIM
Sujet Principal:
Zoonoses
/
Virus de l'hépatite E
/
Hépatite E
/
Génotype
Limites du sujet:
Animals
/
Humans
langue:
En
Texte intégral:
Journal of Veterinary Science
Année:
2016
Type:
Article