Corticobasal Degeneration Presenting as Non-Fluent/Agrammatic Primary Progressive Aphasia: A Case Report
Dementia and Neurocognitive Disorders
; : 55-58, 2016.
Article
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| ID: wpr-11101
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ABSTRACT
BACKGROUND:
Non-fluent agrammatic primary progressive aphasia (naPPA) is characterized by progressive non-fluent speech disorder and might be associated with taupathy such as corticobasal degeneration (CBD) and progressive supranuclear palsy. We report a case of overlap syndrome presented with language impairment, and diagnosed as naPPA with possible CBD. CASE REPORT A 58-year-old woman visited a memory and dementia clinic, with a 10-month history of progressive language disturbance. She was diagnosed as naPPA and overlapping CBD, based on the clinical features and neuroimaging findings including florbetaben PET.CONCLUSIONS:
naPPA is pathologically caused by taupathy, and might progress to asymmetrical parkinsonism and apraxia, suggestive of CBD. Overlapping clinical features in our case represent various phenotypes of taupathy.
Texte intégral:
1
Indice:
WPRIM
Sujet Principal:
Apraxies
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Phénotype
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Paralysie supranucléaire progressive
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Aphasie progressive primaire
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Syndromes parkinsoniens
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Démence
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Neuroimagerie
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Mémoire
Limites du sujet:
Female
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Humans
langue:
En
Texte intégral:
Dementia and Neurocognitive Disorders
Année:
2016
Type:
Article