Primary gastric Hodgkin's lymphoma / 대한외과학회지
Journal of the Korean Surgical Society
; : 111-114, 2012.
Article
Dans En
| WPRIM
| ID: wpr-114024
Responsable en Bibliothèque :
WPRO
ABSTRACT
Gastric Hodgkin's lymphoma is extremely rare. We present a case of primary Hodgkin's lymphoma arising in the stomach of a 65-year-old woman. The patient complained of epigastric discomfort and reflux for one month. Endoscopic examination revealed a protruding lesion characterized by a smooth surface at the antrum. An abdominal computed tomography uncovered a 2.5 x 2.0 cm, exophytic submucosal mass. After the tentative preoperative diagnosis of a gastrointestinal stromal tumor, a gastric wedge resection was performed. Microscopic examination of the mass demonstrated a diffuse proliferation of large atypical lymphoid cells with mono- and binucleated pleomorphic nuclei and prominent nucleoli. Immunohistochemically, the tumor cells were positive for CD30, CD20, and CD79a, whereas they were negative for cytokeratin, carcinoembryonic antigen, CD3, CD15, epithelial membrane antigen, and anaplastic lymphoma kinase-1. Based on the morphological features and immunohistochemical results, in addition to the clinical findings, a diagnosis of primary gastric Hodgkin's lymphoma was established.
Texte intégral:
1
Indice:
WPRIM
Sujet Principal:
Estomac
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Maladie de Hodgkin
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Lymphocytes
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Antigène carcinoembryonnaire
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Antigènes CD30
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Mucine-1
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Tumeurs stromales gastro-intestinales
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Kératines
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Lymphomes
Limites du sujet:
Aged
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Female
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Humans
langue:
En
Texte intégral:
Journal of the Korean Surgical Society
Année:
2012
Type:
Article