Predictors of Relapse in Patients with Organizing Pneumonia / 결핵및호흡기질환
Tuberculosis and Respiratory Diseases
; : 190-195, 2015.
Article
de En
| WPRIM
| ID: wpr-114250
Bibliothèque responsable:
WPRO
ABSTRACT
BACKGROUND: Although organizing pneumonia (OP) responds well to corticosteroid therapy, relapse is common during dose reduction or follow-up. Predictors of relapse in OP patients remain to be established. The aim of the present study was to identify factors related to relapse in OP patients. METHODS: This study was retrospectively performed in a tertiary referral center. Of 66 OP patients who were improved with or without treatment, 20 (30%) experienced relapse. The clinical and radiologic parameters in the relapse patient group (n=20) were compared to that in the non-relapse group (n=46). RESULTS: Multivariate analysis demonstrated that percent predicted forced vital capacity (FVC), PaO2/FiO2, and serum protein level were significant predictors of relapse in OP patients (odds ratio [OR], 0.82; 95% confidence interval [CI], 0.70-0.97; p=0.018; OR, 1.02; 95% CI, 1.00-1.04; p=0.042; and OR, 0.06; 95% CI, 0.01-0.87; p=0.039, respectively). CONCLUSION: This study shows that FVC, PaO2/FiO2 and serum protein level at presentation can significantly predict relapse in OP patients.
Mots clés
Texte intégral:
1
Indice:
WPRIM
Sujet Principal:
Pneumopathie infectieuse
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Récidive
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Capacité vitale
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Analyse multifactorielle
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Études rétrospectives
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Études de suivi
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Pneumonie organisée cryptogénique
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Centres de soins tertiaires
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Méthodes
Type d'étude:
Observational_studies
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Prognostic_studies
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Risk_factors_studies
Limites du sujet:
Humans
langue:
En
Texte intégral:
Tuberculosis and Respiratory Diseases
Année:
2015
Type:
Article