A Case of Pituitary Adenoma with Simultaneous Secretion of TSH and GH
Endocrinology and Metabolism
; : 160-165, 2011.
Article
de En
| WPRIM
| ID: wpr-121312
Bibliothèque responsable:
WPRO
ABSTRACT
Thyrotropin (TSH)-secreting pituitary adenoma is a very rare disease. In one-quarter of patients suffering from this disease, the pituitary tumor secretes other anterior pituitary hormones. Herein, we report a case of pituitary adenoma with simultaneous secretion of TSH and growth hormone (GH). A 34-year-old female visitied local hospital complaining of sweating, intermittent palpitation, and weight loss of 8 kg within 1 year. The patient had undergone trans-sphenoidal surgery 3 years prior for resolution of a TSH and GH co-secreting pituitary adenoma. She had been administered somatostatin analogue prior to visiting our hospital. The patient's GH levels were suppressed to below 1 ng/mL on the 75 g oral glucose tolerance test, and her basal insulin-like growth factor-I (IGF-I) level was within normal range. Thyroid function tests demonstrated increased levels of both free thyroxine and TSH. Sella-MRI revealed pituitary adenoma at the floor of the pituitary fossa, approximately 2 cm in height. Therefore, she was diagnosed with residual TSH-secreting pituitary adenoma. The patient again underwent trans-sphenoidal surgery and entered complete remission, based on hormone levels and MRI findings.
Mots clés
Texte intégral:
1
Indice:
WPRIM
Sujet Principal:
Hormones antéhypophysaires
/
Tumeurs de l'hypophyse
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Valeurs de référence
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Stress psychologique
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Sueur
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Sudation
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Tests de la fonction thyroïdienne
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Thyroxine
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Somatostatine
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Hormone de croissance
Limites du sujet:
Adult
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Female
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Humans
langue:
En
Texte intégral:
Endocrinology and Metabolism
Année:
2011
Type:
Article