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Genetic Diversity among Virulent Mega Plasmids pXO1 and pXO2 of Bacillus anthracis Isolated in Korea
Article de Ko | WPRIM | ID: wpr-128198
Bibliothèque responsable: WPRO
ABSTRACT
We compared genetic variations in virulence mega plasmids pXO1 and pXO2 of twenty-seven Bacillus anthracis strains from Korean patients and environmental samples together with those of Bacillus anthracis Sterne, Pasteur and A2012 standard strains. Genetic variations were analyzed in twenty-three variable regions (ten and thirteen variablenumber tandem repeats and insertion/deletions in pXO1 and pXO2, respectively). The pXO1 plasmids were classified into 7 groups and pXO2 plasmids to 12 groups. Discrete phylogenic lineages could be differentiated between environmental and clinical strains by UPGMA (unweighted pair group method with average) method. In addition, clinical strains showed more variations than environmental isolates. The pXO2 plasmid appeared genetically more unstable than pXO1. A general plasmid genotype could be suggested for Korean soil isolates since they mostly clustered into a representative group.
Sujet(s)
Mots clés
Texte intégral: 1 Indice: WPRIM Sujet Principal: Plasmides / Sol / Bacillus / Bacillus anthracis / Variation génétique / Virulence / Séquences répétées en tandem / Génotype / Corée Limites du sujet: Humans Pays comme sujet: Asia langue: Ko Texte intégral: Journal of Bacteriology and Virology Année: 2003 Type: Article
Texte intégral: 1 Indice: WPRIM Sujet Principal: Plasmides / Sol / Bacillus / Bacillus anthracis / Variation génétique / Virulence / Séquences répétées en tandem / Génotype / Corée Limites du sujet: Humans Pays comme sujet: Asia langue: Ko Texte intégral: Journal of Bacteriology and Virology Année: 2003 Type: Article