Correlation between the Serum Luteinizing Hormone to Folliclestimulating Hormone Ratio and the Anti-Mullerian Hormone Levels in Normo-ovulatory Women
Journal of Korean Medical Science
; : 296-300, 2015.
Article
de En
| WPRIM
| ID: wpr-138281
Bibliothèque responsable:
WPRO
ABSTRACT
Serum anti-Mullerian hormone (AMH) levels are regarded as an age-specific marker for predicting the ovarian reserve in women of reproductive age. Some studies have shown that the luteinizing hormone (LH)/follicle stimulating hormone (FSH) ratio can be used as a predictor of ovarian reserve. The purpose of this study was to assess the variation of LH/FSH ratio with aging and to evaluate the correlation between serum LH/FSH ratio and AMH levels as a predictor of the ovarian reserve in normo-ovulatory women. We retrospectively analyzed the day 3 serum hormone levels in 1,251 patients (age range: 20-50 yr) between January 2010 and January 2011. We divided the patients into 6 groups according to their age. Relation between serum AMH level and LH/FSH ratio was analyzed statistically. The serum AMH level was inversely correlated with age (r = -0.400, P < 0.001). A significant negative correlation was found between serum LH/FSH ratio and age (r = -0.213, P < 0.001). There was a significant partial correlation between serum LH/FSH ratio and AMH level when adjusted by age (r = 0.348, P < 0.001). The LH/FSH ratio could be considered as a useful marker for the ovarian reserve and could be applied to the clinical evaluation with AMH.
Mots clés
Texte intégral:
1
Indice:
WPRIM
Sujet Principal:
Ovulation
/
Vieillissement
/
Hormone lutéinisante
/
Études rétrospectives
/
Hormone antimullérienne
/
Réserve ovarienne
/
Hormone folliculostimulante
/
Menstruation
Type d'étude:
Observational_studies
/
Prognostic_studies
Limites du sujet:
Adult
/
Female
/
Humans
langue:
En
Texte intégral:
Journal of Korean Medical Science
Année:
2015
Type:
Article