Study on Causes of Respiratory Disease to the Middle East Respiratory Syndrome-negative Subjects
Journal of Bacteriology and Virology
; : 156-164, 2017.
Article
Dans Ko
| WPRIM
| ID: wpr-139529
Responsable en Bibliothèque :
WPRO
ABSTRACT
Middle East respiratory syndrome coronavirus (MERS-CoV) causes severe cases of human respiratory disease. The current outbreak of infection with this virus in South Korea, which began on May 20, 2015, has infected 186 patients and caused 36 deaths within 2 months. In this study, to investigate the viral pathogen causing acute respiratory infections, multiplex/RT-PCR was performed on were obtained from nucleic acid of the Middle East Respiratory Syndrome-negative subjects. Viruses and atypical bacteria were detected in 39 of 337 (11.6%). Frequent viruses were human rhinovirus (n=11, 3.3%), human metapneumovirus (n=9, 2.7%), parainfluenza (n=9, 2.7%) and adenovirus (n=4, 1.2%). Mycoplasma pneumonia (M. pneumonia) was detected in 1.8 % (n=6). Out of 9 human metapneumovirus (hMPV) positive samples, 6 samples were successfully sequenced using F gene. And M. pneumoniae was sequencing of a repetitive region of the P1 gene. Phylogenetic analysis revealed that hMPV clustered into A2b lineage (n=4), B2 lineage (n=2) and M. pneumoniae clustered into two genotypes Type 1 (n=4), Type 2a (n=2).
Texte intégral:
1
Indice:
WPRIM
Sujet Principal:
Pneumopathie infectieuse
/
Pneumopathie à mycoplasmes
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Infections de l'appareil respiratoire
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Rhinovirus
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Bactéries
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Séquences répétées d'acides nucléiques
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Adenoviridae
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Infections à Paramyxoviridae
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Metapneumovirus
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Coronavirus du syndrome respiratoire du Moyen-Orient
Type d'étude:
Etiology_studies
Limites du sujet:
Humans
Pays comme sujet:
Asia
langue:
Ko
Texte intégral:
Journal of Bacteriology and Virology
Année:
2017
Type:
Article