Long-Term Complete Remission in an Acute Myeloid Leukemia Patient with Isolated Central Nervous System Relapse after Allogeneic Hematopoietic Stem Cell Transplantation / 영남의대학술지
Yeungnam University Journal of Medicine
; : 96-101, 2012.
Article
Dans Ko
| WPRIM
| ID: wpr-147272
Responsable en Bibliothèque :
WPRO
ABSTRACT
Allogeneic hematopoietic stem cell transplantation (HSCT) is considered the optimal curative treatment for acute myeloid leukemia (AML), but some patients develop bone marrow relapse due to remnant leukemia, and few patients develop extramedullary relapse without bone marrow relapse. Isolated extramedullary relapse (IMER) is defined as extramedullary relapse without bone marrow relapse. IMER has been reported in various sites, including the skin, soft tissue, and central nervous system(CNS). Isolated CNS relapse is relatively rare and is associated with poor prognosis due to the absence of an optimal treatment for it. Reported herein is a case involving an adult AML woman who suffered from isolated extramedullary relapse in the CNS after allogeneic HSCT. She was treated with intrathecal chemotherapy and whole-brain and spine radiotherapy, followed by systemic chemotherapy. She is currently well, with no evidence of leukemia recurrence for over six years.
Texte intégral:
1
Indice:
WPRIM
Sujet Principal:
Pronostic
/
Récidive
/
Peau
/
Rachis
/
Moelle osseuse
/
Cellules souches hématopoïétiques
/
Leucémie aigüe myéloïde
/
Leucémies
/
Système nerveux central
/
Transplantation de moelle osseuse
Type d'étude:
Prognostic_studies
Limites du sujet:
Adult
/
Female
/
Humans
langue:
Ko
Texte intégral:
Yeungnam University Journal of Medicine
Année:
2012
Type:
Article