Rosai-Dorfman Disease in Thoracic Spine: A Rare Case of Compression Fracture
Korean Journal of Spine
; : 198-201, 2014.
Article
Dans En
| WPRIM
| ID: wpr-148276
Responsable en Bibliothèque :
WPRO
ABSTRACT
Sinus histiocytosis with massive lymphadenopathy known as Rosai-Dorfman disease is characterized by painless bilateral cervical lymphadenopathy. Extranodal manifestations are uncommon and spinal involvement is rare. A 15-year-old man presented with intermittent midthoracic back pain only. He had no specific findings on neurologic examinations, hematologic and biochemical laboratory tests. Radiological examination of thoracic spine revealed collapse of T6 vertebrae with thoracic kyphosis and osteolytic lesion of T12 vertebra body. He underwent a removal of bone tumor, anterior reconstruction with mesh and pedicle screw fixation via posterior approach for pathologic confirmation and stabilization. Histopathologic study of the lesion revealed focal infiltration of large histiocytes showing emperipolesis. Immunochemistry stain of histiocytes was positive for CD68 and S-100 but negative for CD1a. This report presents a rare case and literature review of extranodal Rosai-dorfman disease in thoracic spine.
Texte intégral:
1
Indice:
WPRIM
Sujet Principal:
Rachis
/
Immunochimie
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Histiocytose sinusale cytophagique
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Dorsalgie
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Fractures par compression
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Empéripolèse
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Histiocytes
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Cyphose
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Maladies lymphatiques
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Examen neurologique
Limites du sujet:
Adolescent
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Humans
langue:
En
Texte intégral:
Korean Journal of Spine
Année:
2014
Type:
Article