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A Case of Endoscopically Complete Remission of Esophageal Neuroendocrine Tumors by Concurrent Chemoradiation Therapy / 대한소화기학회지
Article de En | WPRIM | ID: wpr-149529
Bibliothèque responsable: WPRO
ABSTRACT
Neuroendocrine tumors (NETs) of the esophagus are extremely rare, aggressive and have a poor prognosis. Combined therapy using chemotherapy, radiotherapy and/or surgery appear effective. Here, we present a patient with a complaint of dysphagia who was diagnosed with this rare tumor. Upper gastrointestinal endoscope of a 46-year-old female revealed a localized ulcerative lesion in the middle esophagus. Histologic exam of biopsy specimens indicated a neuroendocrine carcinoma. The tumor cells were arranged in microtubular structures, with small and round cells containing scanty cytoplasm. They were positive for synaptophysin and chromogranin A on immunohistochemical staining. A computed tomography scan showed an esophageal tumor with enlarged superior mediastinal lymph nodes and about 1.2 cm sized liver metastasis, similar to findings in PET-CT scanning. The patient was prescribed chemotherapy consisting of etoposide and cisplatin, which led to regression of disease on follow-up imaging study. She continues under clinical observation. We seek to increase awareness of this exceedingly rare but hazardous disease by sharing our unexpected finding.
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Texte intégral: 1 Indice: WPRIM Sujet Principal: Pronostic / Radiothérapie / Ulcère / Biopsie / Tumeurs de l'oesophage / Troubles de la déglutition / Études de suivi / Cisplatine / Synaptophysine / Tumeurs neuroendocrines Type d'étude: Observational_studies / Prognostic_studies Limites du sujet: Female / Humans langue: En Texte intégral: Korean J. Gastroenterol. (Online) Année: 2016 Type: Article
Texte intégral: 1 Indice: WPRIM Sujet Principal: Pronostic / Radiothérapie / Ulcère / Biopsie / Tumeurs de l'oesophage / Troubles de la déglutition / Études de suivi / Cisplatine / Synaptophysine / Tumeurs neuroendocrines Type d'étude: Observational_studies / Prognostic_studies Limites du sujet: Female / Humans langue: En Texte intégral: Korean J. Gastroenterol. (Online) Année: 2016 Type: Article