A Case of Endoscopically Complete Remission of Esophageal Neuroendocrine Tumors by Concurrent Chemoradiation Therapy / 대한소화기학회지
Korean J. Gastroenterol. (Online)
; : 265-269, 2016.
Article
de En
| WPRIM
| ID: wpr-149529
Bibliothèque responsable:
WPRO
ABSTRACT
Neuroendocrine tumors (NETs) of the esophagus are extremely rare, aggressive and have a poor prognosis. Combined therapy using chemotherapy, radiotherapy and/or surgery appear effective. Here, we present a patient with a complaint of dysphagia who was diagnosed with this rare tumor. Upper gastrointestinal endoscope of a 46-year-old female revealed a localized ulcerative lesion in the middle esophagus. Histologic exam of biopsy specimens indicated a neuroendocrine carcinoma. The tumor cells were arranged in microtubular structures, with small and round cells containing scanty cytoplasm. They were positive for synaptophysin and chromogranin A on immunohistochemical staining. A computed tomography scan showed an esophageal tumor with enlarged superior mediastinal lymph nodes and about 1.2 cm sized liver metastasis, similar to findings in PET-CT scanning. The patient was prescribed chemotherapy consisting of etoposide and cisplatin, which led to regression of disease on follow-up imaging study. She continues under clinical observation. We seek to increase awareness of this exceedingly rare but hazardous disease by sharing our unexpected finding.
Mots clés
Texte intégral:
1
Indice:
WPRIM
Sujet Principal:
Pronostic
/
Radiothérapie
/
Ulcère
/
Biopsie
/
Tumeurs de l'oesophage
/
Troubles de la déglutition
/
Études de suivi
/
Cisplatine
/
Synaptophysine
/
Tumeurs neuroendocrines
Type d'étude:
Observational_studies
/
Prognostic_studies
Limites du sujet:
Female
/
Humans
langue:
En
Texte intégral:
Korean J. Gastroenterol. (Online)
Année:
2016
Type:
Article