Association of Arterial Stiffness with the Decrease of Post-Dialysis Blood Pressure in Maintained Hemodialysis Patients / 대한신장학회지
Korean Journal of Nephrology
; : 102-109, 2008.
Article
de En
| WPRIM
| ID: wpr-157350
Bibliothèque responsable:
WPRO
ABSTRACT
PURPOSE: Cardiovascular disease is one of the leading causes of mortality and morbidity in hemodialysis patients. Arterial stiffness is known to be associated with vascular calcification in HD patients. Post-dialysis hypotension is a risk factor for cardiovascular mortality. We evaluated the relation between arterial stiffness and post-dialysis blood pressure in maintained HD patients. METHODS: 72 HD patients were enrolled in this study. They had been under maintenance HD for more than 3 months. We checked the biochemical data, including the troponin T, CRP and OPG (osteoprotegerin) levels before their dialysis session and the baPWV (brachio-ankle pulse wave velocity) after the session. We defined post-dialysis BP decrease as a drop of BP of more than 5% of the average MAP for 2 weeks (6 sessions). RESULTS: There were 34 and 38 patients with and without post-dialysis BP decrease, respectively. The BP decrease group had higher CRP, troponin T and OPG levels (p<0.05, 0.01 and 0.01, respectively). The PWV was higher in the BP decrease group (p<0.001). The CRP and troponin T levels were positively correlated with the PWV (r=0.26, p<0.05; r=0.31, p<0.01, respectively). The OPG level was positively correlated with the PWV (r=0.44, p<0.001). Age, pre-dialysis pulse pressure and drops in the patients MAP were correlated with the PWV (r=0.33, p<0.05; r=0.31, p<0.05; r=0.30, p<0.05, respectively). On multivariate analysis, PWV was the independent factor related to the drops in the MAP of the patients (beta=0.311, p=0.021). CONCLUSION: Arterial stiffness is associated with post-dialysis blood pressure decrease.
Mots clés
Texte intégral:
1
Indice:
WPRIM
Sujet Principal:
Pression sanguine
/
Maladies cardiovasculaires
/
Analyse multifactorielle
/
Facteurs de risque
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Dialyse rénale
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Troponine T
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Dialyse
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Athérosclérose
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Calcification vasculaire
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Rigidité vasculaire
Type d'étude:
Etiology_studies
/
Risk_factors_studies
Limites du sujet:
Humans
langue:
En
Texte intégral:
Korean Journal of Nephrology
Année:
2008
Type:
Article