Surgical Outcomes of Bilateral Adrenalectomy / 대한내분비외과학회지
Korean Journal of Endocrine Surgery
; : 234-238, 2013.
Article
de Ko
| WPRIM
| ID: wpr-169063
Bibliothèque responsable:
WPRO
ABSTRACT
PURPOSE: Because the main drawback of bilateral adrenalectomy is permanent adrenal insufficiency and the subsequent risks of life-long steroid use, adrenal preserving partial adrenalectomy is being accepted as its alternative. The aim of this study is to investigate the indications for bilateral adrenalectomy and to assess the postoperative outcomes and steroid replacement according to operative methods. METHODS: From May 1996 through July 2013, a total of 25 patients who underwent bilateral adrenalectomy in our institution were reviewed retrospectively. Surgical outcomes were compared between total and partial adrenalectomy, and postoperative steroid hormone replacement were examined according to the volume of remnant adrenal gland. RESULTS: The median follow-up duration of 25 patients was 55.8 months. The most common indication for bilateral adrenalectomy was bilateral pheochromocytoma (n=16), which was associated with genetic mutation of RET or VHL gene in 11 cases. Cushing's syndrome (n=8) and hyperaldosteronism (n=1) were another indications of bilateral adrenalectomy. Total adrenalectomy was performed in 8 patients and adrenal preserving partial adrenalectomy in 17 patients. Among the 17 patients, only 5 patients needed adrenal hormone replacement and 2 patients had a recurrence at remnant adrenal tissue. CONCLUSION: Adrenal preserving partial adrenalectomy might be a better option for bilateral adrenal tumor than total adrenalectomy because it can reduce complications associated with adrenal insufficiency and recurrence of the disease is not common.
Mots clés
Texte intégral:
1
Indice:
WPRIM
Sujet Principal:
Phéochromocytome
/
Récidive
/
Études rétrospectives
/
Études de suivi
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Insuffisance surrénale
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Glandes surrénales
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Surrénalectomie
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Syndrome de Cushing
/
Hyperaldostéronisme
Type d'étude:
Observational_studies
/
Prognostic_studies
Limites du sujet:
Humans
langue:
Ko
Texte intégral:
Korean Journal of Endocrine Surgery
Année:
2013
Type:
Article