Mortality and Prognostic Factors in Acute Respiratory Distress Syndrome due to Tuberculosis / 대한내과학회지
Korean Journal of Medicine
; : 458-463, 2011.
Article
Dans Ko
| WPRIM
| ID: wpr-169347
Responsable en Bibliothèque :
WPRO
ABSTRACT
BACKGROUND/AIMS:
Acute respiratory distress syndrome (ARDS) due to tuberculosis (TB) is a rare disease, but its mortality is believed to be high. The aim of this study was to evaluate the mortality rate and prognostic factors of ARDS.METHODS:
We retrospectively reviewed the demographic, clinical, radiologic, and laboratory data of 19 patients with ARDS due to active pulmonary TB at Chonnam National University Hospital between January 2000 and December 2010.RESULTS:
The median age of patients was 71.1 (interquartile range [IQR] 51-74) years. None had a history of TB treatment. The most common symptoms were dyspnea (90%), fever (68%), and cough (53%). The overall in-hospital mortality was 73%. The median acute physiologic assessment and chronic health evaluation (APACHE) III score and pneumonia severity index (PSI) were 81.9 (IQR 59.0-92.0) and 111.0 (IQR 77.0-131.0), respectively. The PSI was significantly higher in non-survivors than in survivors (55.0 vs. 122.0; p = 0.016). The rate of TB treatment before admission was significantly higher in survivors than in non-survivors (75% vs. 13%; p = 0.037). The time from admission to treatment initiation was significantly longer in non-survivors than in survivors (3 vs. 0 days; p = 0.049). The median duration of mechanical ventilation was 11 days (IQR 5-16 days). The most common cause of death was a refractory shock (53%).CONCLUSIONS:
The overall mortality rate of ARDS due to pulmonary TB was high. A high PSI score and delay of TB treatment may be risk factors for a poor outcome of ARDS due to pulmonary TB.
Texte intégral:
1
Indice:
WPRIM
Sujet Principal:
Pneumopathie infectieuse
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Ventilation artificielle
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Choc
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Tuberculose
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Indice de gravité de la maladie
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Études rétrospectives
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Facteurs de risque
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Cause de décès
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Mortalité hospitalière
Type d'étude:
Etiology_studies
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Observational_studies
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Prognostic_studies
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Risk_factors_studies
Limites du sujet:
Humans
langue:
Ko
Texte intégral:
Korean Journal of Medicine
Année:
2011
Type:
Article