The Association of Abdominal Fat with Serum Insulin and Atherogenic Index for Obese Females
Journal of the Korean Academy of Family Medicine
; : 917-924, 2002.
Article
Dans Ko
| WPRIM
| ID: wpr-185193
Responsable en Bibliothèque :
WPRO
ABSTRACT
BACKGROUND:
The purpose of this study was to find an independent relationship between waist circumference/waist-to-hip ratio which estimates abdominal fat and fasting insulin/atherogenic index which is a predictor of coronary heart disease in obese women.METHODS:
The subjects were 80 obese (BMI > or = 25 kg/m2) women. Whole body fat was estimated by body fat mass, % body fat using bioelectrical impedence, and by BMI. Abdominal fat was measured by waist circumference (WC) and waist-to-hip ratio. Fasting insulin was examined and atherogenic index was defined asthe ratio of serum total cholesterol to HDL-cholesterol. Independent association between abdominal fat and insulin/AI was analyzed using partial correlation, multiple regression and Hotelling t-test.RESULTS:
Among subjects, 85.7% of obese women had WC greater or equal to 80 cm. The mean BMI was 30.3 kg/m2. The partial correlations between whole body fat and insulin/AI were not significantly different from the partial correlations between abdominal fat and insulin/AI. When age and height were adjusted, partial correlations between abdominal fat and insulin were 0.38 and 0.39. The partial correlations were reduced to 0.15-0.29 after further adjusting for whole body fat. Age and height-adjusted partial correlations between abdominal fat and AI were 0.34 and 0.36. The partial correlations were reduced to 0.11-0.17 when whole body fat was additionally adjusted. Whole body fat explained 9.9-13.7% for variability of insulin; abdominal fat explained 14.2% and 15.9%. Whole body fat explained 12.5-12.8% for variability of AI and abdominal fat explained 11.9%.CONCLUSION:
Most of the obese women showed abdominal obesity. Abdominal fat did not seem to be independently associated with fasting insulin and atherogenic index.
Texte intégral:
1
Indice:
WPRIM
Sujet Principal:
Tissu adipeux
/
Cholestérol
/
Jeûne
/
Maladie coronarienne
/
Rapport taille-hanches
/
Graisse abdominale
/
Tour de taille
/
Obésité abdominale
/
Insuline
/
Obésité
Limites du sujet:
Female
/
Humans
langue:
Ko
Texte intégral:
Journal of the Korean Academy of Family Medicine
Année:
2002
Type:
Article