Enlarged perihepatic lymph nodes reflects histologic and biochemical inflammatory activity of the liver in chronic hepatitis B / 대한내과학회지
Korean Journal of Medicine
; : 40-45, 2001.
Article
de Ko
| WPRIM
| ID: wpr-186208
Bibliothèque responsable:
WPRO
ABSTRACT
BACKGROUND: It is common to find enlarged lymph nodes within hepatoduoedenal ligament during ultrasonography in patients with chronic hepatitis B. But, its clinical significance has not been clearly understood. METHODS: Lymph node volume within the hepatoduodenal ligament in 50 patients with chronic hepatitis B and 15 healthy controls was evaluated using ultrasonography. In patients with chronic hepatitis B, possible correlation of lymph node volume with biochemical tests, hepatitis activity index, and hepatitis B viremia was investigated. RESULTS: One or more lymph nodes were detected in 48 (96%) out of 50 patients with chronic hepatitis B (volume=3.4+/-2.4 mL, mean+/-S.D.) and 2 (13%) out of 15 controls (volume=0.4 mL, 0.6 mL). In chronic hepatitis B, lymph node volume showed a significant correlation with serum AST (r=0.66), ALT (r=0.63), gammaGT (r=0.53), total score of histologic activity index (r=0.59), and necroinflammatory score (r=0.59, p<0.05 for all); but not with fibrosis score and serum hepatitis B viremia. CONCLUSION: Enlarged perihepatic lymph nodes reflects histologic and biochemical inflammatory activity of the liver in chronic hepatitis B.
Mots clés
Texte intégral:
1
Indice:
WPRIM
Sujet Principal:
Virémie
/
Fibrose
/
Échographie
/
Hépatite B chronique
/
Hépatite
/
Hépatite B
/
Hépatite chronique
/
Ligaments
/
Foie
/
Noeuds lymphatiques
Type d'étude:
Diagnostic_studies
Limites du sujet:
Humans
langue:
Ko
Texte intégral:
Korean Journal of Medicine
Année:
2001
Type:
Article