A Case Of Di Guglielmo Syndrome

ABSTRACT

We have experienced a case of Di Guglielmo Syndrome in a 15 years old girl who had the cheif complaints of dizziness, gereral malaise and fine pustules around the nose. It is a systemic hemopathy characterized by abnormal proliferation of defective erythroid and myeloid cells and is a rare disease in childhood. The peripheral blood showed many rubriblasts, myeloblasts, metamyelocytes and bone marrow also showed atypical prorubricytes and bizzar multinucleated rubriblasts. Brief review of related literatures was made.