Reversible Leukoencephlaopathy Caused by Doxifluridine in a Patient with Gastric Cancer
Journal of the Korean Neurological Association
; : 45-48, 2016.
Article
de Ko
| WPRIM
| ID: wpr-20856
Bibliothèque responsable:
WPRO
ABSTRACT
Doxifluridine neurotoxicity is more rare than 5-FU neurotoxicity. We report a case of leukoencephalopathy caused by long-term use of doxifluridine and which was resolved after discontinuation. A 37-year-old woman who had been on doxifluridine for 4 months after gastrectomy presented with dysarthria. Diffusion-weighted MRI imaging revealed multifocal hyperintense lesions in subcortical areas. Her symptoms disappeared after discontinuing doxifluridine, and lesions on follow-up MRI were resolved. These findings suggest that doxifluridine is a plausible cause of reversible leukoencephalopathy.
Mots clés
Texte intégral:
1
Indice:
WPRIM
Sujet Principal:
Tumeurs de l'estomac
/
Imagerie par résonance magnétique
/
Études de suivi
/
Dysarthrie
/
Leucoencéphalopathies
/
Fluorouracil
/
Gastrectomie
Type d'étude:
Observational_studies
/
Prognostic_studies
Limites du sujet:
Adult
/
Female
/
Humans
langue:
Ko
Texte intégral:
Journal of the Korean Neurological Association
Année:
2016
Type:
Article